Favipiravir shows good clinical efficacy in treating COVID-19: official

Favipiravir shows good clinical efficacy in treating COVID-19: official

Source: Xinhua| 2020-03-17 19:48:40|Editor: huaxia

epa04368952 A Fujifilm Holdings employee displays Avigan tablets, an experimental drug developed and manufactured by Japanese drug maker Toyama Chemical Co., Ltd. ,in Tokyo, Japan, 26 August 2014. The generic name of the Avigan drug is Favipiravir. Japanese Chief Cabinet Secretary Yoshihide Suga said on 25 August 2014 during a regular news conference that Japan was ready to provide an experimental drug developed by Japan’s drug manufacturer Toyama Chemical Co., Ltd., subsidiaries under Fujifilm Holdings, to fight against the global tide of the deadly Ebola virus, if the World Health Organization (WHO) requests it. The drug, called Avigan, is a tablet-format anti-influenza drug developed by Toyama Chemical Co Ltd. It was approved in March by the Health Ministry. Avigan inhibits the replication of the virus genetic material inside infected cells, which prevents propagation. This is a new mechanism, compared with previous antiviral drugs that just tackle propagation, according to the company’s website. In early August, the WHO declared the Ebola outbreak an international public health emergency. There is no available cure or vaccine for the deadly virus. The unapproved Ebola drug ZMapp was given to two US aid workers, who are said to have shown strong improvement, and a Spanish missionary priest, who died in Madrid this month. EPA/KIMIMASA MAYAMA

File photo of Favipiravir (EPA photo)

BEIJING, March 17 (Xinhua) — China has completed the clinical research of Favipiravir, an antiviral drug that has shown good clinical efficacy against the novel coronavirus disease (COVID-19), according to an official Tuesday.

Favipiravir, the influenza drug which was approved for clinical use in Japan in 2014, has shown no obvious adverse reactions in the clinical trial, said Zhang Xinmin, director of the China National Center for Biotechnology Development under the Ministry of Science and Technology, at a press conference.

More than 80 patients have participated in the clinical trial in The Third People’s Hospital of Shenzhen, south China’s Guangdong Province, including 35 patients taking Favipiravir and 45 patients on a control group. Results showed that patients receiving Favipiravir treatment turned negative for the virus in a shorter time compared with patients in the control group.

A multi-centered randomized clinical study led by the Zhongnan Hospital of Wuhan University also suggested that the therapeutic effect of Favipiravir is much better than that of the control group.

Favipiravir has been recommended to medical treatment teams and should be included in the diagnosis and treatment plan for COVID-19 as soon as possible, Zhang said.

A Chinese pharmaceutical company has been approved by the National Medical Products Administration to mass-produce the drug and ensure stable supply, Zhang added. 

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